Email updates

Keep up to date with the latest news and content from Antimicrobial Resistance and Infection Control and BioMed Central.

Open Access Highly Accessed Open Badges Letter to the Editor

The rise of carbapenem resistance in Europe: just the tip of the iceberg?

Anna-Pelagia Magiorakos1*, Carl Suetens1, Dominique L Monnet1, Carlo Gagliotti2, Ole E Heuer1 and EARS-Net Coordination Group and EARS-Net participants

Author Affiliations

1 European Centre for Disease Prevention and Control, Tomtebodavägen 11A, Stockholm SE-171 83, Sweden

2 Agenzia Sanitaria e Sociale Regionale Emilia-Romagna, Bologna, Italy

For all author emails, please log on.

Antimicrobial Resistance and Infection Control 2013, 2:6  doi:10.1186/2047-2994-2-6

Published: 14 February 2013


The European Antimicrobial Resistance Surveillance Network (EARS-Net) collects data on carbapenem resistance from invasive bacterial infections. Increasing percentages of carbapenem resistance in K. pneumoniae isolates were reported from progressively more countries in Europe between 2005 and 2010. A trend analysis showed increasing trends for Greece, Cyprus, Hungary and Italy (p < 0.01). EARS-Net collects data on invasive bacterial isolates, which likely correspond to a fraction of the total number of infections. Increasing reports of community cases suggest that dissemination of carbapenem-resistant K. pneumoniae has penetrated into the community. Good surveillance and infection control measures are urgently needed to contain this spread.

Carbapenems; Antimicrobial drug resistance; Gram-negative bacteria; Klebsiella infections; Europe; β-lactamases