The rise of carbapenem resistance in Europe: just the tip of the iceberg?
1 European Centre for Disease Prevention and Control, Tomtebodavägen 11A, Stockholm SE-171 83, Sweden
2 Agenzia Sanitaria e Sociale Regionale Emilia-Romagna, Bologna, Italy
Antimicrobial Resistance and Infection Control 2013, 2:6 doi:10.1186/2047-2994-2-6Published: 14 February 2013
The European Antimicrobial Resistance Surveillance Network (EARS-Net) collects data on carbapenem resistance from invasive bacterial infections. Increasing percentages of carbapenem resistance in K. pneumoniae isolates were reported from progressively more countries in Europe between 2005 and 2010. A trend analysis showed increasing trends for Greece, Cyprus, Hungary and Italy (p < 0.01). EARS-Net collects data on invasive bacterial isolates, which likely correspond to a fraction of the total number of infections. Increasing reports of community cases suggest that dissemination of carbapenem-resistant K. pneumoniae has penetrated into the community. Good surveillance and infection control measures are urgently needed to contain this spread.