Figure 1.

Observed cases and predicted values (from segmented regression model) of monthly vancomycin-resistant Enterococcus (VRE) epidemic cases (infections and colonizations) in the Assistance Publique-Hôpitaux de Paris before (period 1) and after implementation of the institutional VRE infection control programme (periods 2 and 3). In period 1, measures to control cross transmission of endemic MDR such as MRSA were applied, in period 2, a specific strategy to control the spread of emerging MDR was instituted. In period 3, this strategy was maintained as routine.